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Anti-inflammatory – Sandalwood has been shown to mediate its anti-inflammatory properties in multiple ways. This includes activation of cortisol synthesis pathways in the skin, suppressing inflammatory cytokines.
Antioxidant – Sandalwood has been shown to limit oxidative enzymes and exhibit radical scavenging activity. It can protect the skin from oxidative stress and the formation of reactive oxidative species (free radicals), that result in signs of ageing. To know more about the anti-ageing properties of sandalwood in skin care, read our blog on the topic!
Anti-pigmentation- alpha-santalol, a key component of sandalwood was found to be an inhibitor of tyrosinase, a key enzyme in the biosynthetic pathway for the skin pigment melanin, and may potentially act as an inhibitor of abnormal pigmentation associated with ageing and exposure to ultraviolet light. To know more about how sandalwood powder can help reduce tanning and pigmentation, read our blog on the topic!
Anti-microbial – Sandalwood is active against many gram-positive strains of bacteria including some antibiotic-resistant strains of Staphylococcus and some gram-negative bacteria. It has been shown to be effective against Staph (S. aureus, S. pyogenes and S. epidermidis) and Propionibacterium acnes (P. acnes and P. granulosum). It is also a potent antifungal agent.
Anti-cancer – Sandalwood has exhibited anti-proliferative properties in various studies. Sandalwood has been shown to induce autophagy and cell death in proliferating keratinocytes suggesting that it may prevent the progression of pre-cancerous conditions to skin cancer. In one study sandalwood oil exhibited cytotoxicity towards cancerous cells but not towards non-cancerous cells. Sandalwood oil was also shown to promote epidermal wound healing.